left kidneys stained with hematoxylin-eosin (HE; A–D) and Masson's trichrome (E–H) and immunohistochemical images for α-smooth muscle actin (α-SMA; I–L) and transforming growth factor-β (TGF-β; M–P)
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Effects of the antioxidant drug tempol on renal oxygenation in mice with reduced renal mass.
Lai EY, Luo Z, Onozato ML, Rudolph EH, Solis G, Jose PA, Wellstein A, Aslam S, Quinn MT, Griendling K, Le T, Li P, Palm F, Welch WJ, Wilcox CS. Am J Physiol Renal Physiol. 2012 Jul 1;303(1):F64-74. doi: 10.1152/ajprenal.00005.2012. Addition of the antioxidant probucol to angiotensin II type I receptor antagonist arrests progressive mesangioproliferative glomerulonephritis in the rat. Kondo S, Shimizu M, Urushihara M, Tsuchiya K, Yoshizumi M, Tamaki T, Nishiyama A, Kawachi H, Shimizu F, Quinn MT, Lambeth DJ, Kagami S. J Am Soc Nephrol. 2006 Mar;17(3):783-94. |